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    A At this time Health Canada is not requesting that manufacturers submit test reports on DEHP and BPA On September 1 2008 Health Canada will be sending out a survey to ALL manufacturers of licensed Class II III and IV medical devices

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    1 Testing by the ManufacturerThe manufacturer is required to conduct all appropriate tests including bluetongue virus exclusion pseudorabies virus exclusion or replicating avian leukosis virus testing where appropriate described and agreed upon in the OP prior to the release of each serial of a licensed veterinary biologic that is produced or sold in Canada

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    Health Canada Phthalates in Toys It can be concluded that DEHP is causing the most severe reproductive effects in animal studies evaluating toxicity TOTM is also causing reproductive toxicity but in doses more than 20 times higher Similar performance and cost compared to DEHP Hassle free replacement

  • Urinary metabolomic profiling in rats exposed to dietary

    Di 2 ethylhexyl phthalate DEHP exposed animal model The daily food utilization rate and daily food intake in the DEHP exposed group of rats were not significantly different when compared with the control group after 30 days P > 0 05 However the levels of DEHP and MEHP in serum and fat were significantly greater in the DEHP exposed groups compared with the control group P < 0 05 Table 1

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    In January 2002 Health Canada released the Final Report of the Expert Advisory Panel on DEHP in Medical Devices 1 Below is a summary of the Expert Panel s findings The Panel made recommendations based on a 2001 Health Canada review entitled DEHP in Medical Devices An Exposure and Toxicity Assessment 2 and external studies

  • DEHP ExposureB Braun

    Diethylhexylphthalate DEHP is a phthalate a chemical substance that is frequently used to soften PVC Polyvinyl Chloride medical devices such as blood bags tubing catheters and disposable gloves to make materials more pliable and comfortable to use The increasing knowledge of the effects of phthalate exposure which can be teratogenic carcinogenic or induce reproductive toxicity has

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    DRAFT POSITION STATEMENT ON DEHP IN MEDICAL DEVICES FOR STAKEHOLDER CONSULTATION BACKGROUND The Medical Devices Bureau of Health Canada has completed a review of the scientific and medical literature that forms the basis for concerns that Di 2 ethylhexyl phthalate DEHP leached from medical devices may pose health hazards to patients

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    Tips on Buying Infusion Supplies Prescriptions IV fluids always require a prescription in the US In Canada and Mexico IV fluids are over the counter Most vendors will also insist on a prescription for IV admin sets but some will not A few states including Connecticut Illinois Massachusetts New Jersey New York and Rhode Island

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    Health Canada Phthalates in Toys It can be concluded that DEHP is causing the most severe reproductive effects in animal studies evaluating toxicity TOTM is also causing reproductive toxicity but in doses more than 20 times higher Similar performance and cost compared to DEHP Hassle free replacement

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  • Guidance Document Guidance for the Labelling of Canada

    Guidance documents are administrative instruments not having force of law and as such allow for flexibility in approach Alternate approaches to the principles and practices described in this document may be acceptable provided they are supported by adequate scientific justification Alternate approaches should be discussed in advance with the relevant program area to avoid the possible